Classificação das Amiloidoses

Veja matéria completa aqui.

Table-2 

Classifications of Amyloidosis

 

Clinical Classification	Associated Condition	Amyloid Fibril Type	Precursor
Systemic Amyloidosis
Primary or Secondary	Multiple myeloma	AL	Iglambda (or kappa chains)
Secondary	Chronic inflammatory disease __Rheumatoid arthritis __Tuberculosis __Skin and lung abscesses	AA	SAA
Secondary	Cancer Hodgkin's disease	AA	SAA
Secondary	Hemodialysis for CRF(*)	beta2-m(**)	beta2-m
Primary	Heredofamilial amyloidosis __Familial Mediterranean __Fever __Familial amyloid __polyneuropathy	AA   Transthyretin	SAA   Transthyretin(#)
Localized Amyloidosis
	Senile cardiac amyloidosis	Transthyretin	Transthyretin
	Senile cerebral amyloidosis: __Alzheimer's disease	Amyloid beta protein	Amyloid precursor protein (APP)
	Endocrine tumors __Medullary carcinoma __of thyroid	Procaltitonin	Calcitonin
(*): chronic renal failure; (**): beta2-microglobulin is a normal serum protein and a component of MHC class I molecules; (#): transthyretin is a normal serum protein that transports thyroxin and retinol (vitamin A) and is deposited in a variant form.